INT33656

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Context Info
Confidence 0.04
First Reported 1983
Last Reported 1986
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.14
Pain Relevance 1.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ap2m1) mitochondrion (Ap2m1) vesicle-mediated transport (Ap2m1)
plasma membrane (Ap2m1)
Anatomy Link Frequency
central nervous system 1
Ap2m1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 1 98.84 Very High Very High Very High
Enkephalin 3 98.16 Very High Very High Very High
Central nervous system 2 97.40 Very High Very High Very High
narcan 3 97.20 Very High Very High Very High
Opioid 7 91.76 High High
opiate 1 85.28 High High
analgesia 2 75.28 Quite High
opioid receptor 1 75.00 Quite High
depression 1 67.76 Quite High
Analgesic 1 51.36 Quite High
Disease Link Frequency Relevance Heat
Catalepsy 1 72.56 Quite High
Respiratory Failure 1 68.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This is consistent with the high and low affinity sites representing the mu 1 and mu 2 sites respectively.
Gene_expression (representing) of mu 2
1) Confidence 0.04 Published 1986 Journal J. Recept. Res. Section Abstract Doc Link 3012081 Disease Relevance 0 Pain Relevance 0.32
Evidence from a variety of experimental models has suggested the existence of mu 1, mu 2 and delta binding sites for morphine and the enkephalins in the central nervous system.
Gene_expression (existence) of mu 2 in central nervous system associated with central nervous system, enkephalin and morphine
2) Confidence 0.03 Published 1983 Journal Life Sci. Section Abstract Doc Link 6319856 Disease Relevance 0.14 Pain Relevance 0.78

General Comments

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