INT336606

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Mapk8, Map2k1) cytoplasm (Mapk8, Map2k1) cytosol (Mapk8, Map2k1)
nucleus (Mapk8, Map2k1) Golgi apparatus (Map2k1) cell proliferation (Map2k1)
Anatomy Link Frequency
hearts 1
Mapk8 (Mus musculus)
Map2k1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ketamine 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 23 97.46 Very High Very High Very High
Death 7 56.32 Quite High
Apoptosis 2 50.84 Quite High
Bacillus Anthracis Infection 28 50.00 Quite Low
Pressure And Volume Under Development 13 5.00 Very Low Very Low Very Low
Infection 11 5.00 Very Low Very Low Very Low
Cv General 2 Under Development 5 5.00 Very Low Very Low Very Low
Coronary Heart Disease 3 5.00 Very Low Very Low Very Low
Pressure Volume 2 Under Development 3 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Evaluation of stress signaling pathways following in vivo challenge of lethal toxin (2 µg/g, b.w., i.p.) for 18 hrs revealed overtly downregulated MEK1/2, phospho-MAP kinase and phospho-ERK associated with hyperactivation of JNK in murine hearts (Fig. 10).
JNK Binding (associated) of MEK1 in hearts associated with stress
1) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2954163 Disease Relevance 0.72 Pain Relevance 0

General Comments

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