INT336738

Context Info Confidence 0.02 First Reported 2010 Last Reported 2010 Negated 2 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 2.15 Pain Relevance 0.24

extracellular region (S100a8, Ambp) plasma membrane (S100a8, Ambp) transport (Ambp) extracellular space (S100a8) cytoskeleton (S100a8) protein maturation (Ambp)

Anatomy Link Frequency kidney 3 bladder 1 S100a8 (Mus musculus) Ambp (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 26 85.56 Inflammatory mediators 10 80.44 Inflammatory response 12 5.00 chemokine 12 5.00 cytokine 8 5.00 imagery 6 5.00 anesthesia 2 5.00 Versed 2 5.00

Disease Link Frequency Relevance Heat Urinary Tract Infection 84 100.00 Targeted Disruption 82 98.28 Infection 62 90.80 INFLAMMATION 48 85.56 Pneumococcal Infection 6 57.64 Bacterial Respiratory Disease 4 45.92 Urological Neuroanatomy 12 5.00 Sepsis 8 5.00 Disease 6 5.00 Pyelonephritis 4 5.00

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Protein

Mutation

Event

Anatomy

Negation

Speculation

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Disease term

We show that despite high S100A8/A9 expression in bladder and kidney tissue upon UTI, in this model S100A8/A9 does not contribute to an effective host response against E.

S100A8 Neg (not) Regulation (contribute) of Gene_expression (expression) of UTI in kidney associated with urinary tract infection

1) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2954806 Disease Relevance 1.08 Pain Relevance 0.12

We show that despite high S100A8/A9 expression in bladder and kidney tissue upon UTI, in this model S100A8/A9 does not contribute to an effective host response against E.

S100A8 Neg (not) Regulation (contribute) of in bladder Gene_expression (expression) of UTI in kidney associated with urinary tract infection

2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2954806 Disease Relevance 1.08 Pain Relevance 0.12

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