INT336779

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Context Info
Confidence 0.75
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.84
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (ERAP2) endoplasmic reticulum (ERAP2)
ERAP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 2 99.96 Very High Very High Very High
Inflammation 6 24.32 Low Low
spinal inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 12 100.00 Very High Very High Very High
INFLAMMATION 8 99.78 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 8 32.12 Quite Low
Eclampsia 12 15.28 Low Low
Malaria 8 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low
Reprotox - General 1 2 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 2 5.00 Very Low Very Low Very Low
Low Back Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of ERAP2 knock-down is not evident when the antigen-processing machinery is activated by IFN-?
Localization (knock) of ERAP2 associated with targeted disruption
1) Confidence 0.75 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2954825 Disease Relevance 0.42 Pain Relevance 0.04
This suggests that rather than affecting inflammatory response, ERAP2 deficiency might be relevant to basal MHC class I presentation.
Localization (presentation) of ERAP2 associated with inflammatory response
2) Confidence 0.75 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2954825 Disease Relevance 0.42 Pain Relevance 0.05

General Comments

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