INT336866

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Context Info
Confidence 0.65
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.02
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Tcf7) DNA binding (Tcf7)
Anatomy Link Frequency
mature B cells 1
nucleus 1
Tcf7 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 13 37.68 Quite Low
aspirin 14 5.00 Very Low Very Low Very Low
cINOD 6 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 53 89.92 High High
Adenocarcinoma 2 85.16 High High
Targeted Disruption 3 84.52 Quite High
Adenoma 2 84.40 Quite High
Hematological Disease 4 79.84 Quite High
Leukemia 6 61.52 Quite High
Myeloid Leukemia 8 51.20 Quite High
Blast Crisis 1 50.56 Quite High
Hematologic Neoplasms 11 40.00 Quite Low
Repression 2 33.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-catenin pathway on mature B cells is not obvious because they do not express TCF/LEF factors[43].
Neg (not) Gene_expression (express) of TCF in mature B cells
1) Confidence 0.65 Published 2010 Journal J Hematol Oncol Section Body Doc Link PMC2954871 Disease Relevance 0.60 Pain Relevance 0
The Tcf family consists of four members in vertebrates, including Tcf1, Tcf3, Tcf4 and Lef1.
Gene_expression (family) of Tcf
2) Confidence 0.65 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2955614 Disease Relevance 0.26 Pain Relevance 0
-catenin accumulates in the nucleus, Groucho/TLE is displaced from Tcf/Lef by ?
Gene_expression (/) of Tcf in nucleus
3) Confidence 0.65 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2955614 Disease Relevance 0.16 Pain Relevance 0

General Comments

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