INT337078

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Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.30
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Trp53) mitochondrion (Trp53) endoplasmic reticulum (Trp53)
enzyme binding (Trp53) protein complex assembly (Trp53) DNA binding (Trp53)
Trp53 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 20 78.12 Quite High
cytokine 8 62.96 Quite High
cINOD 1 41.68 Quite Low
chemokine 1 12.84 Low Low
cva 1 7.20 Low Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 1 92.08 High High
Apoptosis 3 86.40 High High
Starvation 1 84.24 Quite High
Cancer 41 81.88 Quite High
INFLAMMATION 23 78.12 Quite High
Death 4 76.00 Quite High
Colon Cancer 4 44.12 Quite Low
Infection 2 36.00 Quite Low
Metastasis 3 34.08 Quite Low
Malignant Neoplastic Disease 2 33.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Over-expression of MIF down regulated p53 levels and suppressed nuclear localization, thereby prohibiting its transcriptional activity.
Negative_regulation (suppressed) of Localization (localization) of p53
1) Confidence 0.20 Published 2010 Journal QJM: An International Journal of Medicine Section Body Doc Link PMC2955282 Disease Relevance 1.30 Pain Relevance 0.17

General Comments

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