INT337080

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.00
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pla2g4a) Golgi apparatus (Pla2g4a) endoplasmic reticulum (Pla2g4a)
nucleus (Pla2g4a) cytoplasm (Pla2g4a)
Pla2g4a (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 20 50.00 Quite Low
cytokine 8 39.20 Quite Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 41 96.36 Very High Very High Very High
Hyperplasia 1 85.88 High High
Death 4 82.24 Quite High
Colon Cancer 4 78.80 Quite High
Intestinal Cancer 1 72.56 Quite High
Disease 10 69.44 Quite High
Reprotox - General 1 3 62.08 Quite High
Breast Cancer 4 56.32 Quite High
Malignant Neoplastic Disease 2 53.76 Quite High
INFLAMMATION 23 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This results in downstream activation of cPLA2 and release of the prostaglandin precursor arachadonic acid, a potential substrate for COX-2 now known to be induced as an important element of p53 inhibition by MIF.
Positive_regulation (activation) of Localization (release) of cPLA2
1) Confidence 0.18 Published 2010 Journal QJM: An International Journal of Medicine Section Body Doc Link PMC2955282 Disease Relevance 1.00 Pain Relevance 0

General Comments

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