INT337113

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.28
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ppp1r1b, Cdk5) nucleus (Ppp1r1b, Cdk5) intracellular (Ppp1r1b)
embryo development (Cdk5) cytosol (Cdk5) signal transduction (Ppp1r1b)
Ppp1r1b (Mus musculus)
Cdk5 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 42 75.12 Quite High
antagonist 4 50.56 Quite High
cocaine 10 50.40 Quite High
Nucleus accumbens 18 32.64 Quite Low
Enkephalin 10 5.00 Very Low Very Low Very Low
substance P 10 5.00 Very Low Very Low Very Low
GABAergic 8 5.00 Very Low Very Low Very Low
Dynorphin 6 5.00 Very Low Very Low Very Low
projection neuron 6 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 24 80.16 Quite High
Stress 2 10.56 Low Low
Cognitive Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the other hand, DARPP-32 becomes an inhibitor of PKA when it is phosphorylated on Thr75 by cyclin-dependent kinase 5 (Cdk5).
DARPP-32 Negative_regulation (inhibitor) of Phosphorylation (phosphorylated) of Cdk5
1) Confidence 0.11 Published 2010 Journal Frontiers in Neuroanatomy Section Body Doc Link PMC2955397 Disease Relevance 0.14 Pain Relevance 0.15
On the other hand, DARPP-32 becomes an inhibitor of PKA when it is phosphorylated on Thr75 by cyclin-dependent kinase 5 (Cdk5).
DARPP-32 Negative_regulation (inhibitor) of Phosphorylation (phosphorylated) of cyclin-dependent kinase 5
2) Confidence 0.11 Published 2010 Journal Frontiers in Neuroanatomy Section Body Doc Link PMC2955397 Disease Relevance 0.14 Pain Relevance 0.12

General Comments

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