INT337161

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Context Info
Confidence 0.29
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.78
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Diap1, Iqgap1) cytoplasm (Diap1, Iqgap1) nucleus (Iqgap1)
cytoskeleton (Diap1) cytoskeleton organization (Diap1) protein complex (Iqgap1)
Anatomy Link Frequency
filament 2
Diap1 (Mus musculus)
Iqgap1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 2 79.96 Quite High
ischemia 66 75.24 Quite High
Inflammation 60 73.36 Quite High
cytokine 6 44.96 Quite Low
fibrosis 6 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 4 85.92 High High
INFLAMMATION 62 79.56 Quite High
Cv Unclassified Under Development 66 75.24 Quite High
Vasculitis 2 50.88 Quite High
Necrosis 22 49.44 Quite Low
Cardiovascular Disease 2 28.28 Quite Low
Cancer 6 26.40 Quite Low
Adhesions 22 5.00 Very Low Very Low Very Low
Injury 12 5.00 Very Low Very Low Very Low
Peritonitis 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IQGAP1 also binds to actin filament nucleator, Diaphanous-related formin (Dia1), and thus localizing Dia1 at the actin-rich phagocytic cup, which is required for migration and phagocytosis of RAW macrophage [17].
Dia1 Binding (binds) of IQGAP1 in filament
1) Confidence 0.29 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2955540 Disease Relevance 0.37 Pain Relevance 0.14
IQGAP1 also binds to actin filament nucleator, Diaphanous-related formin (Dia1), and thus localizing Dia1 at the actin-rich phagocytic cup, which is required for migration and phagocytosis of RAW macrophage [17].
Dia1 Binding (binds) of IQGAP1 in filament
2) Confidence 0.21 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2955540 Disease Relevance 0.42 Pain Relevance 0.14

General Comments

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