INT337165

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Iqgap1, VEGFA) protein complex (Iqgap1) extracellular space (VEGFA)
extracellular region (VEGFA) growth (VEGFA) proteinaceous extracellular matrix (VEGFA)
Anatomy Link Frequency
ECs 2
Iqgap1 (Mus musculus)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 30 92.76 High High
ischemia 33 88.00 High High
fibrosis 3 45.20 Quite Low
cytokine 3 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 31 92.76 High High
Injury 6 91.44 High High
Cv Unclassified Under Development 33 88.00 High High
Necrosis 11 46.24 Quite Low
Fibrosis 3 45.20 Quite Low
Targeted Disruption 1 36.64 Quite Low
Adhesions 11 25.00 Low Low
Peritonitis 5 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We previously demonstrated that IQGAP1 mediates vascular endothelial growth factor (VEGF)-induced ROS production and migration of cultured endothelial cells (ECs); however, its role in post-ischemic neovascularization is unknown.


IQGAP1 Positive_regulation (mediates) of Gene_expression (production) of VEGF in ECs
1) Confidence 0.03 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2955540 Disease Relevance 0.27 Pain Relevance 0.09

General Comments

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