INT337210

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.20
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (CD274) signal transduction (CD274) plasma membrane (CD274)
Anatomy Link Frequency
PDL-1 2
CD274 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 2 76.24 Quite High
Inflammation 68 74.72 Quite High
chemokine 14 44.40 Quite Low
Chronic pancreatitis 20 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adenocarcinoma 180 99.36 Very High Very High Very High
Rheumatoid Arthritis 2 76.24 Quite High
Disease 10 75.08 Quite High
INFLAMMATION 68 74.72 Quite High
Pancreatic Cancer 10 67.68 Quite High
Skin Cancer 4 63.04 Quite High
Breast Cancer 8 40.80 Quite Low
Cancer 68 28.24 Quite Low
Hepatitis C Virus Infection 4 27.24 Quite Low
Pancreatitis 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mix of PDAC plasmas did not have any clear effects on CCR7, PDL-1, and DCIR (Figure 10A).
Neg (not) Spec (clear) Regulation (effects) of PDL-1 in PDL-1 associated with adenocarcinoma
1) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2955544 Disease Relevance 0.55 Pain Relevance 0
We found that the negative costimulatory molecules PDL-1 and B7H3 were up regulated ex vivo on blood MDCs and PDCs from PDAC patients and this could be one reason for the impaired immunostimulatory capacity.
Regulation (regulated) of PDL-1 in PDL-1 associated with adenocarcinoma
2) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2955544 Disease Relevance 0.65 Pain Relevance 0.10

General Comments

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