INT337261

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Context Info
Confidence 0.17
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.19
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (E2F1) mitochondrion (E2F1) DNA binding (E2F1)
cytoplasm (E2F1) cell proliferation (E2F1) extracellular region (PRB1)
E2F1 (Homo sapiens)
PRB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 3 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
Gabapentin 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 45 100.00 Very High Very High Very High
Metastasis 9 25.12 Quite Low
Wound Healing 6 5.00 Very Low Very Low Very Low
Repression 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Foreign-body Reaction 3 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 3 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Leukemia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, the roles of E2F-1 in cancer have been well-recognized due to its association with pRB1— a classic tumor suppressor.
E2F-1 Binding (recognized) of pRB1 associated with cancer
1) Confidence 0.17 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2955548 Disease Relevance 0.38 Pain Relevance 0
The pRB1 tumor suppressor directly associates with E2F-1 to modulate gene expression, either inhibit its transactivation or enhance its suppressive function [43], [44], [45], [46].
E2F-1 Binding (associates) of pRB1 associated with cancer
2) Confidence 0.13 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2955548 Disease Relevance 0.43 Pain Relevance 0
Moreover, the roles of E2F-1 in cancer have been well-recognized due to its association with pRB1— a classic tumor suppressor.
E2F-1 Binding (association) of pRB1 associated with cancer
3) Confidence 0.13 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2955548 Disease Relevance 0.38 Pain Relevance 0

General Comments

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