INT337273

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Context Info
Confidence 0.60
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (E2F1) mitochondrion (E2F1) DNA binding (E2F1)
cytoplasm (E2F1) cell proliferation (E2F1) extracellular space (THBS1)
E2F1 (Homo sapiens)
THBS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Gabapentin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 30 17.68 Low Low
Metastasis 6 5.00 Very Low Very Low Very Low
Wound Healing 4 5.00 Very Low Very Low Very Low
Repression 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Foreign-body Reaction 2 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Leukemia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These observations suggested that E2F-1 could regulate TSP1 expression by directly binding to its promoter.
E2F-1 Regulation (regulate) of Gene_expression (expression) of TSP1
1) Confidence 0.60 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2955548 Disease Relevance 0 Pain Relevance 0
We next want to test whether E2F1 could up-regulate expression of the endogenous TSP1 gene.
E2F1 Regulation (regulate) of Gene_expression (expression) of TSP1 gene
2) Confidence 0.44 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2955548 Disease Relevance 0 Pain Relevance 0

General Comments

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