INT337294

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (IRF6, TLR4) cytosol (IRF6) signal transduction (TLR4)
plasma membrane (TLR4) intracellular (TLR4) nucleus (IRF6)
Anatomy Link Frequency
Caco-2 2
IRF6 (Homo sapiens)
TLR4 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 3 33.92 Quite Low
Inflammation 14 33.52 Quite Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 1 91.04 High High
Neonatal Necrotizing Enterocolitis 34 73.28 Quite High
INFLAMMATION 14 33.52 Quite Low
Apoptosis 3 30.56 Quite Low
Injury 10 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Hypoxia 2 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 2 5.00 Very Low Very Low Very Low
Mucositis 2 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several IEC lines, including the Caco-2 cell line, respond minimally to LPS because of very low TLR4 expression [20], [22], [31].
LPS Positive_regulation (respond) of Gene_expression (expression) of TLR4 in Caco-2
1) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2955554 Disease Relevance 0.16 Pain Relevance 0

General Comments

This test has worked.

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