INT337309

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.89
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (PTAFR, IRF6) cytosol (IRF6) nucleolus (PTAFR)
plasma membrane (PTAFR) DNA binding (IRF6) cytoplasm (IRF6)
PTAFR (Homo sapiens)
IRF6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 4 48.48 Quite Low
Inflammation 28 40.48 Quite Low
cytokine 6 31.00 Quite Low
anesthesia 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neonatal Necrotizing Enterocolitis 68 86.84 High High
Injury 20 64.92 Quite High
Colitis 2 59.48 Quite High
INFLAMMATION 28 48.12 Quite Low
Inflammatory Bowel Disease 4 41.04 Quite Low
Apoptosis 6 10.84 Low Low
Disease 6 5.00 Very Low Very Low Very Low
Hypoxia 4 5.00 Very Low Very Low Very Low
Mucositis 4 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Whether the priming effect of PAF on LPS-induced IL-8 secretion can be explained solely by the PAF-induced higher level TLR4 expression or whether PAF also had an effect on TLR4 signaling is yet to be determined.
PAF Spec (whether) Regulation (effect) of Localization (secretion) of LPS
1) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2955554 Disease Relevance 0.47 Pain Relevance 0
Whether the priming effect of PAF on LPS-induced IL-8 secretion can be explained solely by the PAF-induced higher level TLR4 expression or whether PAF also had an effect on TLR4 signaling is yet to be determined.
PAF Regulation (effect) of Localization (secretion) of LPS
2) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2955554 Disease Relevance 0.42 Pain Relevance 0

General Comments

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