INT33731

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Context Info
Confidence 0.41
First Reported 1986
Last Reported 1986
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TRIM13) endoplasmic reticulum (TRIM13) intracellular (TRIM13)
ligase activity (TRIM13) cytoplasm (TRIM13) signal transducer activity (TRIM13)
Anatomy Link Frequency
brain 1
TRIM13 (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 3 100.00 Very High Very High Very High
Opioid 1 92.60 High High
Morphine 2 75.00 Quite High
opioid receptor 2 75.00 Quite High
Potency 1 74.88 Quite High
narcan 1 71.12 Quite High
opiate 1 43.04 Quite Low
Disease Link Frequency Relevance Heat
Neuroblastoma 3 91.80 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Scatchard analysis of [3H]-D-Ala2-D-Leu5-enkephalin (DADLE) in the presence of 10(-5) M D-Pro4-morphiceptin (to block the mu receptors) and the competitive displacement by various highly selective ligands yielded the binding parameters of delta sites which closely resemble those of the delta receptors in brain and mouse neuroblastoma clones.
Negative_regulation (block) of Leu5 in brain associated with neuroblastoma and enkephalin
1) Confidence 0.41 Published 1986 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 3015131 Disease Relevance 0.26 Pain Relevance 0.55

General Comments

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