INT337352

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Context Info
Confidence 0.14
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (ARNT, HIF1A) nucleus (ARNT, HIF1A) transcription factor binding (ARNT, HIF1A)
cytoplasm (ARNT, HIF1A) signal transducer activity (ARNT, HIF1A) signal transduction (HIF1A)
Anatomy Link Frequency
nucleus 1
ARNT (Homo sapiens)
HIF1A (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 10 99.96 Very High Very High Very High
Stress 27 91.12 High High
Aging 6 43.28 Quite Low
Diabetes Mellitus 2 26.00 Quite Low
Apoptosis 6 25.44 Quite Low
Disease 7 23.04 Low Low
Lifespan 1 11.68 Low Low
Cardiovascular Disease 5 5.00 Very Low Very Low Very Low
Nicotine Addiction 4 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Under hypoxia, HIF1A dimerises with ARNT, allowing translocation into the nucleus for induction of gene expression.
ARNT Binding (dimerises) of HIF1A in nucleus associated with hypoxia
1) Confidence 0.14 Published 2010 Journal BMC Med Section Body Doc Link PMC2955589 Disease Relevance 0.61 Pain Relevance 0

General Comments

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