INT337622

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.51 Pain Relevance 0

extracellular region (SERPINB2, F13A1, PLAU) cytoplasm (SERPINB2, F13A1) extracellular space (SERPINB2, PLAU) plasma membrane (SERPINB2, PLAU) Golgi apparatus (SERPINB2) transferase activity, transferring acyl groups (F13A1)

SERPINB2 (Homo sapiens) F13A1 (Homo sapiens) PLAU (Homo sapiens)

Pain Link Frequency Relevance Heat tolerance 1 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Cancer 21 95.04 Metastasis 24 74.92 Skin Cancer 47 53.92 Alzheimer's Dementia 1 20.00 Ovarian Cancer 1 12.24 Mouth Cancer 4 5.00 Disease 3 5.00 Colon Cancer 2 5.00 Advanced Or Metastatic Breast Cancer 1 5.00 Cervical Cancer 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Several other proteins, fibrin, uPA receptor (uPAR), and two main PA inhibitors, PAI-1 and PAI-2, are also important in this process.

PAI-2 Positive_regulation (important) of fibrin Binding (receptor) of uPA

1) Confidence 0.01 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2956083 Disease Relevance 0.51 Pain Relevance 0

General Comments

This test has worked.