INT337692

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Cyp2b2) endoplasmic reticulum (Cyp2b2) DNA binding (Nr1i3)
cytoplasm (Nr1i3) cytosol (Nr1i3) oxidoreductase activity (Cyp2b2)
Anatomy Link Frequency
CAR 1
Cyp2b2 (Rattus norvegicus)
Nr1i3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anticonvulsant 1 97.42 Very High Very High Very High
Inflammation 6 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertrophy 1 98.36 Very High Very High Very High
Toxicity 11 81.16 Quite High
Shock 1 46.00 Quite Low
Nephrotoxicity 1 27.32 Quite Low
INFLAMMATION 7 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, administration of anticonvulsant phenobarbital to rats causes liver hypertrophy, which is associated with induction of hepatic drug metabolizing enzymes such as CYP2B and CYP3A through the activation of the nuclear receptor CAR [4].
CYP2B Positive_regulation (activation) of nuclear receptor CAR in CAR associated with hypertrophy and anticonvulsant
1) Confidence 0.00 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2956103 Disease Relevance 0.31 Pain Relevance 0.05

General Comments

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