INT337742

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Context Info
Confidence 0.38
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 1.72
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SLC2A2) endosome (SLC2A2) small molecule metabolic process (SLC2A2)
plasma membrane (SLC2A2) carbohydrate metabolic process (SLC2A2) transmembrane transport (SLC2A2)
Anatomy Link Frequency
liver 4
SLC2A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 132 86.44 High High
tolerance 1 28.40 Quite Low
cytokine 8 5.00 Very Low Very Low Very Low
Inflammatory response 8 5.00 Very Low Very Low Very Low
Bile 8 5.00 Very Low Very Low Very Low
COX2 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Paracetamol 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 8 99.92 Very High Very High Very High
Diabetes Mellitus 100 99.22 Very High Very High Very High
Fatty Liver 12 76.52 Quite High
Obesity 172 75.68 Quite High
Body Weight 4 69.68 Quite High
Hyperglycemia 12 58.00 Quite High
Toxicity 40 5.00 Very Low Very Low Very Low
Hepatotoxicity 36 5.00 Very Low Very Low Very Low
Hepatocellular Cancer 32 5.00 Very Low Very Low Very Low
Apoptosis 32 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Analysis of 42 genes associated with diabetes by RT q-PCR showed that in the liver, expression of Gk, Glut-2, apolipoprotein A-IV (ApoA-IV), PPAR?
Gene_expression (expression) of Glut-2 in liver associated with diabetes mellitus and disorder of lipid metabolism
1) Confidence 0.38 Published 2010 Journal PPAR Research Section Body Doc Link PMC2963138 Disease Relevance 0.73 Pain Relevance 0.14
, sterol regulatory element binding protein 1 (Srebp1), phosphoenolpyruvate carboxykinase (Pepck), and glucose transporter type 2 (Glut-2 or Slc2a2) expression levels, leading to the conclusion that there is an adipogenic conversion of the liver when PPAR?
Gene_expression (expression) of Glut-2 in liver
2) Confidence 0.33 Published 2010 Journal PPAR Research Section Body Doc Link PMC2963138 Disease Relevance 0.33 Pain Relevance 0
, sterol regulatory element binding protein 1 (Srebp1), phosphoenolpyruvate carboxykinase (Pepck), and glucose transporter type 2 (Glut-2 or Slc2a2) expression levels, leading to the conclusion that there is an adipogenic conversion of the liver when PPAR?
Gene_expression (expression) of glucose transporter type 2 in liver
3) Confidence 0.33 Published 2010 Journal PPAR Research Section Body Doc Link PMC2963138 Disease Relevance 0.34 Pain Relevance 0
, sterol regulatory element binding protein 1 (Srebp1), phosphoenolpyruvate carboxykinase (Pepck), and glucose transporter type 2 (Glut-2 or Slc2a2) expression levels, leading to the conclusion that there is an adipogenic conversion of the liver when PPAR?
Gene_expression (expression) of Slc2a2 in liver
4) Confidence 0.33 Published 2010 Journal PPAR Research Section Body Doc Link PMC2963138 Disease Relevance 0.33 Pain Relevance 0
In particular, cocultured NPI showed a statistically significant increase of the expression of PDX-1, Glucokinase (GK), and GLUT-2 as compared to controls (P < .050).

3.4.

Gene_expression (expression) of GLUT-2
5) Confidence 0.17 Published 2010 Journal Stem Cells International Section Body Doc Link PMC2956457 Disease Relevance 0 Pain Relevance 0

General Comments

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