INT337793

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 4.29
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Dgkb) kinase activity (Dgkb) cytoplasm (Dgkb)
Anatomy Link Frequency
arm 2
Dgkb (Mus musculus)
Pain Link Frequency Relevance Heat
Eae 66 99.16 Very High Very High Very High
depression 9 57.76 Quite High
antidepressant 6 52.88 Quite High
alcohol 6 12.72 Low Low
Hippocampus 9 10.72 Low Low
Kinase C 15 5.00 Very Low Very Low Very Low
cerebral cortex 6 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
member 8 3 5.00 Very Low Very Low Very Low
Pyramidal cell 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 48 100.00 Very High Very High Very High
Attention Deficit Hyperactivity Disorder 30 100.00 Very High Very High Very High
Targeted Disruption 252 99.84 Very High Very High Very High
Schizophrenia 9 96.92 Very High Very High Very High
Toxicity 3 94.96 High High
Manic Depressive Disorder 45 93.04 High High
Mental Disorders 9 90.96 High High
Depression 15 57.76 Quite High
Cognitive Disorder 9 24.40 Low Low
Congenital Anomalies 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the open field test, LiCl at 100 mg/kg or more significantly attenuated the hyperactivity of DGK?
Negative_regulation (attenuated) of DGK Binding (hyperactivity) of associated with eae and attention deficit hyperactivity disorder
1) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 1.73 Pain Relevance 0.09
Low-dose lithium treatment did not reduce the activity of DGK?
Neg (not) Negative_regulation (reduce) of DGK Neg (not) Binding (activity) of
2) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 1.25 Pain Relevance 0.11
KO mice displayed enhanced open arm selectivity, which also indicates lowered anxiety of DGK?
Negative_regulation (lowered) of DGK Binding (anxiety) of in arm associated with targeted disruption and anxiety disorder
3) Confidence 0.36 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 1.31 Pain Relevance 0.28

General Comments

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