INT337806

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Context Info
Confidence 0.53
First Reported 2010
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 4.53
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Dgkb) kinase activity (Dgkb) cytoplasm (Dgkb)
Anatomy Link Frequency
spine 1
Dgkb (Mus musculus)
Pain Link Frequency Relevance Heat
Eae 88 94.40 High High
Hippocampus 12 89.00 High High
cerebral cortex 8 87.92 High High
Dopamine 4 82.64 Quite High
Kinase C 20 76.12 Quite High
member 8 4 66.20 Quite High
depression 12 64.24 Quite High
alcohol 8 37.24 Quite Low
antidepressant 8 27.04 Quite Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 336 99.84 Very High Very High Very High
Anxiety Disorder 64 95.28 Very High Very High Very High
Manic Depressive Disorder 60 88.08 High High
Neurodegenerative Disease 4 77.52 Quite High
Mental Disorders 12 75.12 Quite High
Depression 20 64.24 Quite High
Disease 4 60.72 Quite High
Attention Deficit Hyperactivity Disorder 40 58.80 Quite High
Cognitive Disorder 12 54.64 Quite High
Schizophrenia 12 45.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
regulates spine formation by regulating lipids, and DGK?
Regulation (regulating) of DGK in spine
1) Confidence 0.53 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 0.78 Pain Relevance 0.29
To investigate the effect of lithium on fearless behavior of DGK?
Spec (investigate) Regulation (effect) of DGK
2) Confidence 0.39 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 1.34 Pain Relevance 0.15
In addition, lithium significantly attenuated the alteration of these phosophorylation levels in DGK?
Regulation (alteration) of DGK
3) Confidence 0.39 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 1.00 Pain Relevance 0.08
On the other hand, other drugs, such as haloperidol (0.1 mg/kg, i.p.), diazepam (1.0 mg/kg, i.p.), or imipramine (20 mg/kg, i.p.), did not affect the lcomotoer activity of DGK?
Neg (not) Regulation (affect) of DGK
4) Confidence 0.27 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 1.42 Pain Relevance 0.18

General Comments

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