INT337808

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Context Info
Confidence 0.66
First Reported 2010
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 15
Disease Relevance 13.46
Pain Relevance 1.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Dgkb) kinase activity (Dgkb) cytoplasm (Dgkb)
Anatomy Link Frequency
cortex 5
striatum 1
hippocampus 1
Dgkb (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 45 99.54 Very High Very High Very High
Eae 330 97.52 Very High Very High Very High
Kinase C 75 91.08 High High
cerebral cortex 30 90.00 High High
Dopamine 15 90.00 High High
Pyramidal cell 15 83.76 Quite High
member 8 15 68.28 Quite High
alcohol 30 63.36 Quite High
depression 45 59.68 Quite High
antidepressant 30 48.04 Quite Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 240 99.98 Very High Very High Very High
Targeted Disruption 1260 99.84 Very High Very High Very High
Congenital Anomalies 60 94.56 High High
Cleidocranial Dysplasia 30 91.76 High High
Manic Depressive Disorder 225 90.80 High High
Sprains And Strains 15 84.80 Quite High
Attention Deficit Hyperactivity Disorder 150 83.68 Quite High
Schizophrenia 45 75.92 Quite High
Cognitive Disorder 45 75.64 Quite High
Mental Disorders 45 73.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The phenotypes of DGK?
Gene_expression (phenotypes) of DGK
1) Confidence 0.66 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 0.69 Pain Relevance 0.07
were decreased in the cortex of DGK?
Gene_expression (cortex) of DGK in cortex
2) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 0.96 Pain Relevance 0.07
proteins in the hippocampus and striatum were not different between WT mice and DGK?
Neg (not) Gene_expression (different) of DGK in striatum associated with hippocampus
3) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 0.73 Pain Relevance 0.10
The phosphorylation level of Akt (Thr308) was also decreased in the cortex of DGK?
Gene_expression (cortex) of DGK in cortex
4) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 0.91 Pain Relevance 0.08
In the present study, we performed a comprehensive behavioral analysis of DGK?
Gene_expression (analysis) of DGK
5) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 1.23 Pain Relevance 0.07
KO mice was significantly decreased when compared with vehicle-treated DGK?
Gene_expression (treated) of DGK associated with targeted disruption
6) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 1.33 Pain Relevance 0.08
Our present study revealed that impaired spine formation also occurred in the cortex of DGK?
Gene_expression (cortex) of DGK in cortex
7) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 0.43 Pain Relevance 0.08
In addition, we and other researchers previously demonstrated that DGK?
Gene_expression (demonstrated) of DGK
8) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 0.73 Pain Relevance 0.29
The phosphorylation level of Akt (Thr308) was also decreased in the cortex of DGK?
Gene_expression (cortex) of DGK in cortex
9) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 0.61 Pain Relevance 0.08
Indeed, using DGK?
Gene_expression (using) of DGK
10) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 1.08 Pain Relevance 0.07
were decreased in the cortex of DGK?
Gene_expression (cortex) of DGK in cortex
11) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 0.73 Pain Relevance 0.09
Next, DGK?
Gene_expression (Next) of DGK
12) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 0.77 Pain Relevance 0.20
KO mice, and the results revealed that DGK?
Gene_expression (revealed) of DGK associated with targeted disruption
13) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 1.05 Pain Relevance 0.13
To further assess anxiety levels of DGK?
Gene_expression (levels) of DGK associated with anxiety disorder
14) Confidence 0.52 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 1.49 Pain Relevance 0.06
proteins in the hippocampus and striatum were not different between WT mice and DGK?
Neg (not) Gene_expression (different) of DGK in hippocampus associated with hippocampus
15) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956634 Disease Relevance 0.73 Pain Relevance 0.10

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