INT337889

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ins1, Ldlrap1) cytosol (Ldlrap1) extracellular space (Ins1)
extracellular region (Ins1) carbohydrate metabolic process (Ins1) lipid metabolic process (Ldlrap1)
Ins1 (Mus musculus)
Ldlrap1 (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropeptide 3 81.76 Quite High
Central nervous system 3 74.32 Quite High
agonist 10 46.40 Quite Low
Intracerebroventricular 13 5.60 Low Low
bDMF 6 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 2 99.52 Very High Very High Very High
Hypoglycemia 3 61.40 Quite High
Obesity 6 56.36 Quite High
Hyperphagia 2 55.88 Quite High
Body Weight 6 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Impaired Glucose Tolerance 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Weight Loss 1 5.00 Very Low Very Low Very Low
Hyperinsulinism 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Upon binding to its receptor in the ARH, insulin triggers a repression of the AgRP and NPY gene expression and an increase in POMC gene expression [26], [42].
insulin Binding (binding) of ARH associated with repression
1) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956692 Disease Relevance 0.27 Pain Relevance 0.08

General Comments

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