INT338039

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.52
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Prkca) endoplasmic reticulum (Prkca) enzyme binding (Prkca)
protein complex (Prkca) cytoplasm (Prkca) cytosol (Prkca)
Anatomy Link Frequency
sensory neurons 2
F2 (Mus musculus)
Prkca (Mus musculus)
Pain Link Frequency Relevance Heat
nociceptor 16 99.60 Very High Very High Very High
Inflammation 12 93.36 High High
Analgesic 2 85.88 High High
Antinociceptive 4 79.56 Quite High
substance P 5 46.44 Quite Low
Pain 6 39.64 Quite Low
Calcitonin gene-related peptide 20 5.00 Very Low Very Low Very Low
Nerve growth factor 14 5.00 Very Low Very Low Very Low
qutenza 14 5.00 Very Low Very Low Very Low
agonist 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 13 93.36 High High
Pressure And Volume Under Development 1 90.92 High High
Nervous System Injury 1 77.28 Quite High
Increased Venous Pressure Under Development 1 71.84 Quite High
Injury 3 62.96 Quite High
Coagulation Disorder 2 61.08 Quite High
Targeted Disruption 3 58.72 Quite High
Nociception 21 50.00 Quite Low
Pain 6 39.64 Quite Low
Sprains And Strains 1 17.28 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To the best of our knowledge no studies have investigated the localization of functional PAR1, 3 and 4 receptors in sensory neurons, nor the role of receptors activated by thrombin in TRPV1 sensitisation or in activation of PKC?
thrombin Positive_regulation (activated) of Positive_regulation (activation) of PKC in sensory neurons
1) Confidence 0.04 Published 2010 Journal Mol Pain Section Body Doc Link PMC2956715 Disease Relevance 0.52 Pain Relevance 0.27

General Comments

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