INT338048

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (Pard3) cytoplasm (Pard3) signal transducer activity (F2rl3)
lipid binding (Pard3) signal transduction (F2rl3) plasma membrane (F2rl3)
Anatomy Link Frequency
neurons 1
F2rl3 (Mus musculus)
Pard3 (Mus musculus)
Pain Link Frequency Relevance Heat
nociceptor 16 57.68 Quite High
bradykinin 4 41.16 Quite Low
qutenza 14 39.04 Quite Low
agonist 14 7.04 Low Low
Calcitonin gene-related peptide 20 5.00 Very Low Very Low Very Low
Nerve growth factor 14 5.00 Very Low Very Low Very Low
Neuropeptide 12 5.00 Very Low Very Low Very Low
Inflammation 12 5.00 Very Low Very Low Very Low
imagery 7 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nociception 21 50.60 Quite High
INFLAMMATION 13 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Coagulation Disorder 2 5.00 Very Low Very Low Very Low
Neurogenic Inflammation 2 5.00 Very Low Very Low Very Low
Rupture 2 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Functional responses to thrombin, which should activate PAR3 (along with PAR1 and PAR4), are seen in a significantly lower number of neurons, however, suggesting that PAR3 is non-functional, at least when expressed in the absence of other PARs.
PAR4 Positive_regulation (activate) of PAR3 in neurons
1) Confidence 0.11 Published 2010 Journal Mol Pain Section Body Doc Link PMC2956715 Disease Relevance 0.05 Pain Relevance 0.11

General Comments

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