INT338055

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (F2) extracellular space (F2) extracellular region (F2)
Anatomy Link Frequency
mast cell 1
F2 (Mus musculus)
Par2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 12 67.60 Quite High
Pain 6 66.24 Quite High
substance P 5 53.20 Quite High
Calcitonin gene-related peptide 20 5.00 Very Low Very Low Very Low
nociceptor 16 5.00 Very Low Very Low Very Low
Nerve growth factor 14 5.00 Very Low Very Low Very Low
qutenza 14 5.00 Very Low Very Low Very Low
agonist 14 5.00 Very Low Very Low Very Low
Neuropeptide 12 5.00 Very Low Very Low Very Low
imagery 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 3 89.72 High High
INFLAMMATION 13 67.60 Quite High
Pain 6 66.24 Quite High
Nociception 21 50.00 Quite Low
Coagulation Disorder 2 23.68 Low Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Neurogenic Inflammation 2 5.00 Very Low Very Low Very Low
Rupture 2 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PAR1, PAR3, and PAR4 are activated by thrombin, reviewed in [5,6], while PAR2 is not activated by thrombin but is activated by trypsin and mast cell tryptase [7-9].
thrombin Neg (not) Positive_regulation (activated) of PAR2 in mast cell
1) Confidence 0.08 Published 2010 Journal Mol Pain Section Body Doc Link PMC2956715 Disease Relevance 0.22 Pain Relevance 0.13

General Comments

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