INT338162

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Context Info
Confidence 0.49
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Nxnl1) protein targeting (YWHAQ) nucleolus (YWHAQ)
nucleus (YWHAQ) protein complex (YWHAQ) cytoplasm (YWHAQ)
Anatomy Link Frequency
cone cells 2
YWHAQ (Homo sapiens)
Nxnl1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ketamine 3 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 1 99.26 Very High Very High Very High
Retina Disease 23 83.08 Quite High
Targeted Disruption 5 50.00 Quite Low
Blindness 3 5.00 Very Low Very Low Very Low
Metabolic Disorder 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Overdose 1 5.00 Very Low Very Low Very Low
Rod Or Cone Dystrophy 1 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It could involve an indirect mechanism related to the metabolism of cone cells that are starving after rod death [37] or, more directly, a mechanism requiring the interaction of the Nxnl1 gene product with the microtubule interacting protein TAU [38], or both.
Positive_regulation (requiring) of protein TAU Binding (interaction) of Nxnl1 in cone cells associated with death
1) Confidence 0.49 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2957406 Disease Relevance 0.26 Pain Relevance 0

General Comments

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