INT338170

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Context Info
Confidence 0.44
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.96
Pain Relevance 2.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (CDKN2A) DNA binding (CDKN2A) protein complex (CDKN2A)
cytoplasm (CDKN2A) cytosol (CDKN2A) nucleolus (CDKN2A)
CDKN2A (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 316 98.18 Very High Very High Very High
addiction 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Melanoma 308 98.64 Very High Very High Very High
Disease 10 22.28 Low Low
Sunburn 28 12.56 Low Low
Burns 14 10.40 Low Low
Nevus 62 7.28 Low Low
Cancer 22 5.00 Very Low Very Low Very Low
Skin Cancer 8 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Retinoblastoma 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also investigated whether the associations of the frequent MC1R variants and number of MC1R variants with melanoma risk differed according to the type of CDKN2A mutations (mutations affecting p16INK4a protein only vs mutations affecting both p16INK4a and p14ARF proteins).
Regulation (affecting) of Regulation (affecting) of p14ARF associated with melanocortin 1 receptor and melanoma
1) Confidence 0.44 Published 2010 Journal JNCI Journal of the National Cancer Institute Section Body Doc Link PMC2957428 Disease Relevance 0.48 Pain Relevance 1.23
We also investigated whether the associations of the frequent MC1R variants and number of MC1R variants with melanoma risk differed according to the type of CDKN2A mutations (mutations affecting p16INK4a protein only vs mutations affecting both p16INK4a and p14ARF proteins).
Regulation (affecting) of Regulation (affecting) of p16INK4a associated with melanocortin 1 receptor and melanoma
2) Confidence 0.44 Published 2010 Journal JNCI Journal of the National Cancer Institute Section Body Doc Link PMC2957428 Disease Relevance 0.48 Pain Relevance 1.23

General Comments

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