INT338428

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.75
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

anatomical structure formation involved in morphogenesis (Gata3) cell morphogenesis (Gata3) DNA binding (Gata3)
extracellular space (Il4) signal transduction (Gata3) extracellular region (Il4)
Il4 (Mus musculus)
Gata3 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 45 94.08 High High
Inflammation 26 88.60 High High
fibrosis 3 20.16 Low Low
chemokine 6 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 104 99.40 Very High Very High Very High
Disease 14 93.08 High High
INFLAMMATION 27 88.60 High High
Hypersensitivity 24 78.88 Quite High
Airway Remodeling 6 62.48 Quite High
Eosinophilia 8 60.48 Quite High
Fibrosis 3 20.16 Low Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Occupational Lung Diseases 4 5.00 Very Low Very Low Very Low
Hyperplasia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-4 upregulates the fate-determining transcription factor GATA-3 in naïve T helper cells and is therefore essential for the initial differentiation and expansion of allergen-specific TH2 cells [3].
IL-4 Positive_regulation (upregulates) of GATA-3
1) Confidence 0.06 Published 2010 Journal Journal of Allergy Section Body Doc Link PMC2957587 Disease Relevance 0.75 Pain Relevance 0.13

General Comments

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