INT338430

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.27
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cd4) nucleus (Ik) plasma membrane (Cd4)
enzyme binding (Cd4)
Anatomy Link Frequency
blood 2
Cd4 (Mus musculus)
Ik (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 45 100.00 Very High Very High Very High
Inflammation 26 86.84 High High
tolerance 3 68.88 Quite High
chemokine 6 54.24 Quite High
fibrosis 3 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 104 96.60 Very High Very High Very High
Genetic Predisposition To Disease 1 88.20 High High
INFLAMMATION 27 86.84 High High
Hypersensitivity 24 86.04 High High
Disease 14 79.00 Quite High
Autoimmune Disease 3 62.68 Quite High
Obesity 1 26.48 Quite Low
Eosinophilia 8 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Airway Remodeling 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several studies demonstrated that CD4+/CD25+ T cells are able to inhibit cytokine production and proliferation of TH2 cells in vitro and to suppress development of experimental asthma including AHR in mice [131, 132]; however, in asthmatic patients, the number of these cells appeared to be significantly decreased in peripheral blood, airway tissue, and BAL fluid.
CD4 Negative_regulation (inhibit) of Gene_expression (production) of cytokine in blood associated with asthma and cytokine
1) Confidence 0.01 Published 2010 Journal Journal of Allergy Section Body Doc Link PMC2957587 Disease Relevance 1.27 Pain Relevance 0.22

General Comments

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