INT338432

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.63
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il23a, IL8) extracellular region (Il23a, IL8) signal transduction (IL8)
intracellular (IL8)
Anatomy Link Frequency
eosinophils 4
Il23a (Mus musculus)
IL8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 52 92.72 High High
cytokine 90 13.56 Low Low
chemokine 12 5.00 Very Low Very Low Very Low
fibrosis 6 5.00 Very Low Very Low Very Low
tolerance 6 5.00 Very Low Very Low Very Low
Neuritis 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 208 98.20 Very High Very High Very High
INFLAMMATION 54 92.72 High High
Rhinitis 6 91.92 High High
Eczema 2 83.68 Quite High
Bacterial Respiratory Disease 4 39.76 Quite Low
Bacterial Infection 2 38.08 Quite Low
Viral Infection 2 31.12 Quite Low
Hypersensitivity 48 5.00 Very Low Very Low Very Low
Disease 28 5.00 Very Low Very Low Very Low
Eosinophilia 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The authors demonstrated that IL-23 in combination with IL-17A and IL-17F promoted the production of CXCL1 and IL-8 in human eosinophils generating a strong neutrophilotactic signal, whereas IL-23 together with IL-17F alone induced the production of IL-1?
IL-23 Positive_regulation (promoted) of Gene_expression (production) of IL-8 in eosinophils
1) Confidence 0.01 Published 2010 Journal Journal of Allergy Section Body Doc Link PMC2957587 Disease Relevance 0.82 Pain Relevance 0.05
The authors demonstrated that IL-23 in combination with IL-17A and IL-17F promoted the production of CXCL1 and IL-8 in human eosinophils generating a strong neutrophilotactic signal, whereas IL-23 together with IL-17F alone induced the production of IL-1?
IL-23 Positive_regulation (promoted) of Gene_expression (production) of IL-8 in eosinophils
2) Confidence 0.01 Published 2010 Journal Journal of Allergy Section Body Doc Link PMC2957587 Disease Relevance 0.81 Pain Relevance 0.05

General Comments

This test has worked.

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