INT338495

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Context Info
Confidence 0.69
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.86
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (RNLS) extracellular region (RNLS)
RNLS (Homo sapiens)
Pain Link Frequency Relevance Heat
Catecholamine 30 99.98 Very High Very High Very High
Parenteral administration 2 93.12 High High
ischemia 36 83.60 Quite High
monoamine 2 33.20 Quite Low
imagery 4 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chronic Renal Failure 2 98.88 Very High Very High Very High
Cardiovascular Disease 2 95.64 Very High Very High Very High
Coronary Artery Disease 24 84.24 Quite High
Cv Unclassified Under Development 32 78.88 Quite High
Myocardial Infarction 12 78.88 Quite High
Renal Disease 8 78.80 Quite High
Coronary Heart Disease 32 77.80 Quite High
Hypertension 10 57.60 Quite High
Left Ventricular Hypertrophy 12 11.76 Low Low
Death 2 5.04 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Brief surges in catecholamine levels increase the activity, secretion, and synthesis of renalase resulting in accelerated degradation of catecholamines via a negative feedback mechanism.
Positive_regulation (increase) of Gene_expression (synthesis) of renalase associated with catecholamine
1) Confidence 0.69 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2958117 Disease Relevance 0.38 Pain Relevance 0.21
Excess catecholamines promote the activity, secretion, and synthesis of renalase, providing a novel pathway of negative-feedback homeostatic control [8].
Positive_regulation (promote) of Gene_expression (synthesis) of renalase associated with catecholamine
2) Confidence 0.46 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2958117 Disease Relevance 0.48 Pain Relevance 0.19

General Comments

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