INT338718

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Context Info
Confidence 0.04
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NOTCH1) nucleoplasm (NOTCH1) extracellular region (NOTCH1)
Golgi apparatus (NOTCH1) plasma membrane (NOTCH1) nucleus (NOTCH1)
Anatomy Link Frequency
Notch 2
NOTCH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 1 62.72 Quite High
cINOD 2 50.96 Quite High
imagery 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 83 79.12 Quite High
Genomic Instability 3 77.56 Quite High
Glioma 1 70.80 Quite High
Colon Cancer 1 67.64 Quite High
Medulloblastoma 2 67.36 Quite High
Chronic Lymphoid Leukemia 1 55.12 Quite High
INFLAMMATION 1 50.48 Quite High
Leukemia 6 47.60 Quite Low
Glioblastoma 6 18.96 Low Low
Malignant Neoplastic Disease 3 5.40 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The Notch ligands, Jagged 1 & 2 and Delta1 (D1) to Delta3 (D3), induce the release of the Notch intracellular (Notch-IC) domain via enzymatic proteolytic cleavage by ?
Positive_regulation (induce) of Localization (release) of Notch in Notch
1) Confidence 0.04 Published 2011 Journal Journal of Oncology Section Body Doc Link PMC2958340 Disease Relevance 0.60 Pain Relevance 0.13

General Comments

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