INT338787

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (HAMP) nucleus (SYCP3) cell cycle (SYCP3)
DNA binding (SYCP3) cell division (SYCP3) cytoplasm (HAMP)
SYCP3 (Homo sapiens)
HAMP (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 1 86.36 High High
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Iron Overload 1 97.88 Very High Very High Very High
Hypoxia 1 87.04 High High
INFLAMMATION 1 86.36 High High
Anaemia 10 9.88 Low Low
Hepatocellular Cancer 3 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 3 5.00 Very Low Very Low Very Low
Contagious Ecthyma 2 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low
Skin Cancer 1 5.00 Very Low Very Low Very Low
Fever 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Under physiological conditions, TMPRSS6 down-regulates hepcidin levels by binding and proteolytically degrading the hepcidin activator and BMP co-receptor HJV (haemojuvelin), a protein mutated in hereditary haemochromatosis type 2 [13].
co-receptor Regulation (regulates) of hepcidin associated with iron overload
1) Confidence 0.11 Published 2010 Journal Biochemical Journal Section Body Doc Link PMC2958558 Disease Relevance 0.27 Pain Relevance 0.04

General Comments

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