INT338860

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Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid metabolic process (PAFAH1B2) cytoplasm (PAFAH1B2)
Anatomy Link Frequency
platelet 1
PAFAH1B2 (Homo sapiens)
Pain Link Frequency Relevance Heat
bDMF 16 22.00 Low Low
Lamotrigine 23 5.00 Very Low Very Low Very Low
depression 11 5.00 Very Low Very Low Very Low
carbamazepine 9 5.00 Very Low Very Low Very Low
anticonvulsant 8 5.00 Very Low Very Low Very Low
gABA 7 5.00 Very Low Very Low Very Low
Gabapentin 7 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
Dopamine 5 5.00 Very Low Very Low Very Low
Glutamate 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Manic Depressive Disorder 125 58.44 Quite High
Cancer 1 40.20 Quite Low
Apoptosis 4 35.64 Quite Low
Neuroblastoma 3 19.04 Low Low
Depression 14 5.00 Very Low Very Low Very Low
Recurrence 8 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low
Adverse Drug Reaction 6 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low
Psychosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As for lithium-specific effects, the most significant altered expressions were reported for the BCL-2 associated X protein (BAX) and the platelet-activating factor acetylhydrolase isoform 1b, beta subunit (PAFAH1B2).

3.2.

Positive_regulation (activating) of PAFAH1B2 in platelet
1) Confidence 0.20 Published 2010 Journal Human Genomics and Proteomics : HGP Section Body Doc Link PMC2958627 Disease Relevance 0.06 Pain Relevance 0

General Comments

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