INT338861

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (SIX1) nucleus (SIX1) DNA binding (SIX1)
SIX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Glutamate 4 66.40 Quite High
Gabapentin 7 64.96 Quite High
ischemia 1 52.32 Quite High
Lamotrigine 23 49.28 Quite Low
gABA 7 40.92 Quite Low
Glutamate receptor 3 29.40 Quite Low
antagonist 1 28.32 Quite Low
Hippocampus 4 17.28 Low Low
Central nervous system 5 14.44 Low Low
bDMF 16 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuroblastoma 3 92.00 High High
Apoptosis 4 87.12 High High
Cancer 1 77.76 Quite High
Cv Unclassified Under Development 1 52.32 Quite High
Manic Depressive Disorder 125 40.96 Quite Low
Epilepsy 1 33.20 Quite Low
Depression 14 5.00 Very Low Very Low Very Low
Recurrence 8 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low
Adverse Drug Reaction 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Findings showed that the treatment with both drugs determined an altered expression of 936 genes with the homeodomain protein Six1 being the most significantly upregulated.
Positive_regulation (upregulated) of Six1
1) Confidence 0.13 Published 2010 Journal Human Genomics and Proteomics : HGP Section Body Doc Link PMC2958627 Disease Relevance 0.47 Pain Relevance 0.18

General Comments

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