INT338877

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Impa1) mitochondrion (Impa1) nucleolus (Impa1)
nucleus (Impa1) cytoplasm (Impa1)
Impa1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Central nervous system 5 80.12 Quite High
imagery 1 67.44 Quite High
Hippocampus 4 48.56 Quite Low
Anterior cingulate 1 44.40 Quite Low
Lamotrigine 23 5.00 Very Low Very Low Very Low
bDMF 16 5.00 Very Low Very Low Very Low
depression 11 5.00 Very Low Very Low Very Low
carbamazepine 9 5.00 Very Low Very Low Very Low
anticonvulsant 8 5.00 Very Low Very Low Very Low
gABA 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Manic Depressive Disorder 125 77.56 Quite High
Depression 14 24.60 Low Low
Recurrence 8 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low
Adverse Drug Reaction 6 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Psychosis 4 5.00 Very Low Very Low Very Low
Neuroblastoma 3 5.00 Very Low Very Low Very Low
Drug Dependence 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Early reports show that lithium directly inhibits two enzymes of the inositol pathway, the inositol monophosphate phosphatase (IMPase) and the inositol polyphosphate 1 phosphatase (IPPase), at therapeutic serum concentration (0.6–1.2?
Negative_regulation (inhibits) of IMPase
1) Confidence 0.19 Published 2010 Journal Human Genomics and Proteomics : HGP Section Body Doc Link PMC2958627 Disease Relevance 0.08 Pain Relevance 0.10

General Comments

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