INT338893

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TNFSF14, Gria1) cytosol (Gria1) signal transduction (TNFSF14)
extracellular space (TNFSF14) extracellular region (TNFSF14) endoplasmic reticulum (Gria1)
Anatomy Link Frequency
neurons 2
TNFSF14 (Homo sapiens)
Gria1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Lamotrigine 23 100.00 Very High Very High Very High
Calcium channel 2 98.76 Very High Very High Very High
Glutamate 4 97.04 Very High Very High Very High
Gabapentin 7 90.92 High High
gABA 7 90.24 High High
Central nervous system 5 86.80 High High
anticonvulsant 8 85.44 High High
Hippocampus 4 81.76 Quite High
bDMF 16 66.48 Quite High
antagonist 1 59.60 Quite High
Disease Link Frequency Relevance Heat
Manic Depressive Disorder 125 88.48 High High
Urological Neuroanatomy 1 80.12 Quite High
Death 1 74.96 Quite High
Apoptosis 4 74.72 Quite High
Lymphatic System Cancer 1 71.52 Quite High
Neuroblastoma 3 66.56 Quite High
Epilepsy 1 49.76 Quite Low
Neurodegenerative Disease 4 21.04 Low Low
Cv Unclassified Under Development 1 11.44 Low Low
Depression 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, LTG significantly enhanced the surface expression of GluR1/2 AMPA receptor in a time- and dose-dependent manner in cultured hippocampal neurons [132].
LTG Positive_regulation (enhanced) of Gene_expression (expression) of GluR1 in neurons associated with lamotrigine
1) Confidence 0.07 Published 2010 Journal Human Genomics and Proteomics : HGP Section Body Doc Link PMC2958627 Disease Relevance 0.59 Pain Relevance 0.94

General Comments

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