INT338894

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.54
Pain Relevance 1.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNFSF14, Gsk3a) cytosol (Gsk3a) extracellular space (TNFSF14)
extracellular region (TNFSF14) plasma membrane (TNFSF14) carbohydrate metabolic process (Gsk3a)
TNFSF14 (Homo sapiens)
Gsk3a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Lamotrigine 23 100.00 Very High Very High Very High
gABA 7 97.44 Very High Very High Very High
Hippocampus 4 94.68 High High
antagonist 1 92.16 High High
Central nervous system 5 91.84 High High
Glutamate receptor 3 90.72 High High
Glutamate 4 84.00 Quite High
Calcium channel 2 81.56 Quite High
Gabapentin 7 73.72 Quite High
anticonvulsant 8 68.24 Quite High
Disease Link Frequency Relevance Heat
Neuroblastoma 3 99.12 Very High Very High Very High
Epilepsy 1 82.32 Quite High
Manic Depressive Disorder 125 71.28 Quite High
Urological Neuroanatomy 1 62.92 Quite High
Death 1 57.76 Quite High
Apoptosis 4 57.52 Quite High
Lymphatic System Cancer 1 54.32 Quite High
Cv Unclassified Under Development 1 44.00 Quite Low
Depression 14 5.00 Very Low Very Low Very Low
Recurrence 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
LTG was also shown to inhibit GSK-3?
LTG Negative_regulation (inhibit) of GSK-3 associated with lamotrigine
1) Confidence 0.00 Published 2010 Journal Human Genomics and Proteomics : HGP Section Body Doc Link PMC2958627 Disease Relevance 0.54 Pain Relevance 1.04

General Comments

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