INT338900

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (MYC, TP73) transcription factor binding (MYC, TP73) nucleoplasm (MYC)
DNA binding (MYC) protein complex (MYC) cytoplasm (TP73)
Anatomy Link Frequency
platelet 2
MYC (Homo sapiens)
TP73 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 2 51.20 Quite High
addiction 2 50.00 Quite Low
dexamethasone 1 45.28 Quite Low
Kinase C 2 29.12 Quite Low
aspirin 1 5.00 Very Low Very Low Very Low
Gabapentin 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
bradykinin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 2 84.80 Quite High
Targeted Disruption 1 67.88 Quite High
Apoptosis 2 65.44 Quite High
Avian Sarcoma 1 54.52 Quite High
Thrombocytopenia 1 38.80 Quite Low
Purpura 1 37.76 Quite Low
Cardiovascular Disease 12 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Renal Artery Obstruction 1 5.00 Very Low Very Low Very Low
Pre-eclampsia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus there are minimal effects on circulating platelet levels. cMYC binds to and induces expression of (no. 6) p73, and both together downregulate PDGF beta receptors [63].
cMYC Positive_regulation (induces) of Gene_expression (expression) of p73 in platelet
1) Confidence 0.05 Published 2010 Journal Human Genomics and Proteomics : HGP Section Body Doc Link PMC2958630 Disease Relevance 0.27 Pain Relevance 0.03

General Comments

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