INT338933

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Context Info
Confidence 0.54
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Fpgs) biosynthetic process (Fpgs) ligase activity (Fpgs)
cytoplasm (Fpgs)
Fpgs (Mus musculus)
Pain Link Frequency Relevance Heat
methotrexate 70 90.68 High High
Glutamate 2 69.00 Quite High
adenocard 8 59.72 Quite High
Inflammation 2 57.00 Quite High
Arthritis 27 50.00 Quite Low
antagonist 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 11 71.20 Quite High
INFLAMMATION 2 57.00 Quite High
Juvenile Chronic Polyarthritis 23 50.00 Quite Low
Cancer 2 43.08 Quite Low
Death 1 42.68 Quite Low
Toxicity 22 5.00 Very Low Very Low Very Low
Disease 11 5.00 Very Low Very Low Very Low
Adverse Drug Reaction 4 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vitro studies have revealed that the cellular response to folate deprivation is associated with increased expression of FPGS and decreased expression of ABCG2 [35], suggesting that the adaptive cellular response to low folate involves increased polyglutamation to promote the retention of folate.
Gene_expression (expression) of FPGS
1) Confidence 0.54 Published 2010 Journal Human Genomics and Proteomics : HGP Section Body Doc Link PMC2958653 Disease Relevance 0.13 Pain Relevance 0.37

General Comments

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