INT339115

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Context Info
Confidence 0.43
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.11
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (ERBB2) signal transduction (ERBB2) plasma membrane (ERBB2)
nucleus (ERBB2) cytoplasm (ERBB2)
ERBB2 (Homo sapiens)
PVT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 58 5.00 Very Low Very Low Very Low
Neuropathic pain 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 48 100.00 Very High Very High Very High
Cancer 160 99.56 Very High Very High Very High
Colon Cancer 2 82.52 Quite High
Skin Cancer 2 54.36 Quite High
Carcinoma 2 27.76 Quite Low
Lobular Carcinoma 2 17.04 Low Low
INFLAMMATION 58 5.00 Very Low Very Low Very Low
Metastasis 6 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When aCGH and RNA data were combined (Additionnal file 1-Table S7A), TRPS1 and PVT1 were found associated with ER+ ERBB2-amplified tumors (Table 1).


ERBB2 Binding (associated) of PVT1 associated with cancer
1) Confidence 0.43 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.30 Pain Relevance 0
Coamplification of MYC and PVT1 seem to correlate with rapidly growing and progressive breast cancer and has been associated with poor outcome in postmenopausal or ERBB2-positive BC patients [59].
ERBB2 Binding (associated) of PVT1 associated with breast cancer
2) Confidence 0.32 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.81 Pain Relevance 0

General Comments

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