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Context Info
Confidence 0.49
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.49
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (ERBB2) signal transduction (ERBB2) plasma membrane (ERBB2)
nucleus (ERBB2) cytoplasm (ERBB2)
ERBB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 31 86.24 High High
palliative 2 55.84 Quite High
imagery 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 13 100.00 Very High Very High Very High
Advanced Or Metastatic Breast Cancer 6 96.72 Very High Very High Very High
Cancer 100 94.80 High High
INFLAMMATION 29 86.24 High High
Apoptosis 2 82.36 Quite High
Recurrence 3 79.72 Quite High
Breast Cancer 72 64.16 Quite High
Adhesions 1 40.08 Quite Low
Inflammatory Breast Neoplasms 2 38.96 Quite Low
Carcinoma 1 25.08 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inclusion of taxanes, aromatase inhibitors, as well as trastuzumab (for HER2-positive disease) becomes implemented at these levels as well.
Positive_regulation (implemented) of Localization (disease) of HER2 associated with disease
1) Confidence 0.49 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC3010663 Disease Relevance 0.83 Pain Relevance 0.06
Geldanamycin could be included in the panel of potential therapeutic tools because it destabilizes ERBB2 tyrosine kinase and suppresses WNT/?
Positive_regulation (destabilizes) of Localization (kinase) of ERBB2
2) Confidence 0.46 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.66 Pain Relevance 0.11

General Comments

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