INT339188

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Context Info
Confidence 0.36
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.45
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (STARD3) endosome (STARD3) transport (STARD3)
lipid metabolic process (STARD3) cytoplasm (STARD3)
STARD3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 58 5.00 Very Low Very Low Very Low
Neuropathic pain 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 160 98.32 Very High Very High Very High
Breast Cancer 48 79.68 Quite High
Lobular Carcinoma 2 71.84 Quite High
INFLAMMATION 58 5.00 Very Low Very Low Very Low
Metastasis 6 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 4 5.00 Very Low Very Low Very Low
Adenocarcinoma 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the 17q12-q21.2 amplicon, which exhibited the highest frequency (Additionnal file 1-Tables S6A-S6B), amplifications combined to the upregulated gene expression of CRKRS (71%), STARD3 (82%), PERLD1 (86%), ERBB2 (92%), C17orf37 (84%) and GRB7 (86%) were the most frequent (Additionnal file 1-Tables S6A-S6B).
Positive_regulation (upregulated) of Gene_expression (expression) of STARD3
1) Confidence 0.36 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.14 Pain Relevance 0
Amplification and overexpression of other genes (such as GRB7, C17orf37 and STARD3) of the 17q12 region could contribute to tumor growth [18,19].
Positive_regulation (overexpression) of Gene_expression (overexpression) of STARD3 associated with cancer
2) Confidence 0.36 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.31 Pain Relevance 0

General Comments

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