INT339253

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Context Info
Confidence 0.25
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (KISS1, GNRH1) signal transduction (GNRH1) extracellular space (GNRH1)
cytoskeleton organization (KISS1) cell-cell signaling (GNRH1)
Anatomy Link Frequency
median eminence 2
KISS1 (Homo sapiens)
GNRH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 1 72.56 Quite High
opiate 1 32.00 Quite Low
gABA 3 31.20 Quite Low
noradrenaline 1 29.36 Quite Low
Neurotransmitter 2 26.64 Quite Low
Neuropeptide 1 25.76 Quite Low
depression 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 1 68.68 Quite High
Hypogonadotropic Hypogonadism 3 63.52 Quite High
Precocious Puberty 4 45.44 Quite Low
Obesity 5 5.92 Low Low
Cancer 3 5.00 Very Low Very Low Very Low
Weight Gain 3 5.00 Very Low Very Low Very Low
Osteoporosis 2 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Anxiety Disorder 2 5.00 Very Low Very Low Very Low
Insulin Resistance 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, Ramaswamy et al reported that, in primates, kisspeptin-beaded axons, surprisingly, made only infrequent contacts with GnRH neurons in the mediobasal hypothalamus, whereas, kisspeptin and GnRH axons were found in extensive and intimate association in the median eminence indicating that nonsynaptic communication at the level of the median eminence is a pathway contributing to the regulation of GnRH release by kisspeptin [12].
kisspeptin Regulation (regulation) of Localization (release) of GnRH in median eminence
1) Confidence 0.25 Published 2010 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2958977 Disease Relevance 0.24 Pain Relevance 0.04

General Comments

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