INT339254

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Context Info
Confidence 0.24
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (GNRH1) extracellular space (GNRH1) extracellular region (GNRH1)
plasma membrane (GNRHR) cell-cell signaling (GNRH1) signal transducer activity (GNRHR)
Anatomy Link Frequency
neurons 1
GNRHR (Homo sapiens)
GNRH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 1 92.04 High High
opiate 1 51.48 Quite High
gABA 3 50.68 Quite High
noradrenaline 1 48.84 Quite Low
Neurotransmitter 2 46.12 Quite Low
Neuropeptide 1 45.24 Quite Low
depression 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 1 88.16 High High
Hypogonadotropic Hypogonadism 3 71.68 Quite High
Precocious Puberty 4 9.04 Low Low
Obesity 5 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Weight Gain 3 5.00 Very Low Very Low Very Low
Osteoporosis 2 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Anxiety Disorder 2 5.00 Very Low Very Low Very Low
Insulin Resistance 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Kisspeptin and GPR54 are expressed in hypothalamic GnRH neurons, suggesting that both GnRHR and GPR54 may act as paracrine and/or autocrine regulators of GnRH neuronal function [11].
GnRHR Regulation (regulators) of GnRH in neurons
1) Confidence 0.24 Published 2010 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2958977 Disease Relevance 0.23 Pain Relevance 0.12

General Comments

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