INT33926

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Context Info
Confidence 0.31
First Reported 1986
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Cpe) extracellular space (Cpe) Golgi apparatus (Cpe)
Anatomy Link Frequency
brain 2
band 2
Cpe (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 5 100.00 Very High Very High Very High
Neuropeptide 3 77.44 Quite High
Thalamus 2 70.64 Quite High
Kinase C 15 67.52 Quite High
Dopamine 31 50.00 Quite Low
gABA 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
cocaine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 3 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
Drug Dependence 2 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Schizophrenia 1 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Differential ontogeny of rat brain peptidases: prenatal expression of enkephalin convertase and postnatal development of angiotensin-converting enzyme.
Negative_regulation (development) of Gene_expression (expression) of enkephalin convertase in brain associated with enkephalin
1) Confidence 0.31 Published 1986 Journal Brain Res. Section Title Doc Link 3021286 Disease Relevance 0 Pain Relevance 0.52
However, coexpression of CPE inhibited the disappearance of the DAT-positive band at 12 hours but was still completely degraded at 24 hours.


Negative_regulation (inhibited) of Gene_expression (coexpression) of CPE in band
2) Confidence 0.26 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0.07

General Comments

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