INT339293

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.87
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Casp1) cell death (Casp1) extracellular region (Casp1)
nucleus (Casp1) intracellular (Casp1) protein complex (Casp1)
Casp1 (Mus musculus)
Il1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 28 98.64 Very High Very High Very High
Inflammation 106 96.08 Very High Very High Very High
IPN 12 88.56 High High
chemokine 8 77.12 Quite High
Arthritis 4 73.04 Quite High
Inflammatory mediators 2 61.08 Quite High
carrageenan induced 2 25.00 Low Low
antagonist 6 5.00 Very Low Very Low Very Low
withdrawal 6 5.00 Very Low Very Low Very Low
reflex sympathetic dystrophy 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperalgesia 6 98.08 Very High Very High Very High
INFLAMMATION 110 96.08 Very High Very High Very High
Inflammatory Pain 12 88.56 High High
Bacterial Infection 2 83.12 Quite High
Nociception 26 79.36 Quite High
Necrosis 8 74.92 Quite High
Cancer 8 74.56 Quite High
Arthritis 4 73.04 Quite High
Disease 2 64.88 Quite High
Urological Neuroanatomy 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Caspase-1 is a cysteine protease responsible for the processing and secretion of IL-1?
Caspase-1 Regulation (responsible) of Localization (secretion) of IL-1
1) Confidence 0.07 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC2959021 Disease Relevance 0.49 Pain Relevance 0.28
Caspase-1 (previously known as IL-1 converting enzyme -ICE) is a member of the caspase family of proteases and is responsible for the processing and secretion of IL-1?
Caspase-1 Regulation (responsible) of Localization (secretion) of IL-1
2) Confidence 0.07 Published 2010 Journal Mol Pain Section Body Doc Link PMC2959021 Disease Relevance 1.38 Pain Relevance 0.55

General Comments

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