INT339387

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Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 5
Disease Relevance 2.39
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Lipe) mitochondrion (Lipe) extracellular space (Lipe)
lipid particle (Lipe) plasma membrane (Lipe) nucleus (Lipe)
Anatomy Link Frequency
adipose tissue 4
Lipe (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 105 96.08 Very High Very High Very High
Inflammation 95 82.88 Quite High
Inflammatory response 35 36.48 Quite Low
anesthesia 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 200 99.68 Very High Very High Very High
Disorder Of Lipid Metabolism 15 83.92 Quite High
INFLAMMATION 130 82.88 Quite High
Syndrome 25 35.12 Quite Low
Endotoxemia 5 10.00 Low Low
Stress 15 5.00 Very Low Very Low Very Low
Shock 15 5.00 Very Low Very Low Very Low
Cancer 10 5.00 Very Low Very Low Very Low
Body Weight 5 5.00 Very Low Very Low Very Low
Necrosis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Figure 5 shows HSL (Figure 5a) and Perilipin (Figure 5b) protein expression in the adipose tissue.
Gene_expression (expression) of HSL in adipose tissue associated with obesity
1) Confidence 0.20 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2959201 Disease Relevance 0.26 Pain Relevance 0.06
The protein expression of HSL was increased and that of Perilipin, decreased in the adipose in R in relation to the control.
Gene_expression (expression) of HSL
2) Confidence 0.17 Published 2010 Journal Lipids Health Dis Section Abstract Doc Link PMC2959201 Disease Relevance 0.65 Pain Relevance 0.26
and IL-10) levels and Toll Like Receptor 4 (TLR4), Nuclear Factor kBp65 (NF-kBp65), Hormone Sensitive Lipase (HSL) and, Perilipin protein expression were assessed in the adipose tissue.
Gene_expression (expression) of HSL in adipose tissue associated with obesity
3) Confidence 0.17 Published 2010 Journal Lipids Health Dis Section Abstract Doc Link PMC2959201 Disease Relevance 0.63 Pain Relevance 0.32
We have demonstrated that an overtraining protocol in rats promoted increases in both IL-6 and IL-10 protein concentration in the white adipose tissue and activated the TLR4 and NF-kBp65 pathways as well as HSL and Perilipin protein expression.
Gene_expression (expression) of HSL in adipose tissue associated with obesity
4) Confidence 0.17 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2959201 Disease Relevance 0.21 Pain Relevance 0.03
and IL-10) levels and Toll Like Receptor 4 (TLR4), Nuclear Factor kBp65 (NF-kBp65), Hormone Sensitive Lipase (HSL) and, Perilipin protein expression were assessed in the adipose tissue.
Gene_expression (expression) of Hormone Sensitive Lipase in adipose tissue associated with obesity
5) Confidence 0.17 Published 2010 Journal Lipids Health Dis Section Abstract Doc Link PMC2959201 Disease Relevance 0.64 Pain Relevance 0.33

General Comments

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